Audrey Summers-Sias was reported missing on Wednesday from West Town on the Near West Side, according to Chicago police.
Summers-Sias, who has schizophrenia, is 5-foot-6 and 180 pounds with brown eyes, curly dark-brown hair, and a fair complexion.
She was last seen in the 800 block of West Washington Boulevard, wearing a green windbreaker jacket, dark pants and black shoes, Chicago police said.
Chicago Police are asking for help in locating a 57-year-old woman. Anyone who knows her whereabouts is asked to call Area South detectives at 312-747-8274.